SON Formula®

The most nutritious and the most health-preserving in comparison
to any dietary protein, protein supplement or amino acid formula.

SON Formula® is a medical food. Medical foods are required by statute to be administered under the supervision of a physician, but there is no requirement for a prescription.

The Discovery of SON Formula®

In 1992, the International Nutrition Research Center, an American leading research institute in the field of human nutrition, led by Prof. Dr. Maurizio Lucà-Moretti, published four comparative, double-blind, triple and quintuple-crossover clinical Net Nitrogen Utilization (NNU) studies conducted in human subjects, while ingesting SON Formula®, as total substitute for dietary proteins1-4.

The scientific evidence obtained from the results of the previously described scientific studies1-4 showed and confirmed the discovery of SON Formula® (map master amino acid pattern®), considered to be one of the most important scientific nutritional breakthroughs of the 20th century.  


World Recognition of the SON Formula® Discovery

Since 1992, a total of forty-five clinical studies performed in human subjects1-45 while ingesting SON Formula®, as a partial or total substitute for dietary proteins, have been published.

Considering the scientific evidence previously described, it can be concluded, that this is the highest number of scientific publications of clinical studies conducted in human subjects1-45 ever published in reference to any dietary protein, protein supplement, or amino acid formula.

In recognition of SON Formula® (map master amino acid pattern®) originality and unprecedented nutritional effectiveness, numerous patents have been granted by the following 30 countries: the United States of America, Canada, Japan, Austria, Belgium, Bulgaria, Croatia, Republic of Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Poland, Portugal, Romania, Slovakia, Slovenia, Spain and Sweden.

Considering the scientific evidence previously described, it can be concluded, that is the highest number of patents granted by the highest number of countries, in recognition of SON Formula® (map master amino acid pattern®) originality and unprecedented nutritional effectiveness, in comparison to any dietary protein, protein supplement or amino acid formula.


SON Formula® Uniqueness

The scientific evidence obtained from the publication of forty-five published comparative clinical studies conducted in human subjects1-45 have shown and confirmed that the use of SON Formula®, as a partial or total substitute for dietary proteins, is:

  • the most nutritious and the most health-preserving

in comparison to any dietary protein, protein supplement or amino acid formula.

The Unique Characteristics of SON Formula®

1. SON Formula® provides a unique, unprecedented, Body Protein Synthesis (BPS = 99% NNU/23 min), namely the highest in comparison to any dietary protein, protein supplement or amino acid formula.  

Comparative clinical Net Nitrogen Utilization (NNU) studies performed in human subjects1-4 have shown and confirmed that the use of SON Formula® provides an unprecedented and unique BPS = 99% NNU/23 min*. On the contrary, dietary proteins provide a BPS of 16-32% NNU/180-360 min. That is, a BPS 24 to 96 times lower compared to that of SON Formula®. As a result, it can be concluded that SON Formula® provides a BPS that is 24 to 96 times higher in comparison to that provided by any dietary protein, protein supplement or amino acid formula.

Bar graph comparing BPS of SON Formula and dietary proteins/protein supplements.

*To illustrate: the Body Protein Synthesis (BPS = %NNU/min), is the scientific index that defines a specific dietary protein nutritional value. Therefore, the higher a dietary protein BPS, the higher its nutritional value, and vice versa.

Considering the scientific evidence1-4 previously described, it can be concluded that SON Formula® is the most nutritious in comparison to any dietary protein, protein supplement or amino acid formula.

2. SON Formula® requires less than 23 minutes to be digested. That is, the shortest digestion time ever required in comparison to any dietary protein, protein supplement or amino acid formula.

Comparative clinical studies conducted in human subjects1-4 have shown that SON Formula® requires less than 23 minutes to be digested. On the contrary, dietary proteins require a digestion time of 180 to 360 minutes (3 to 6 hours). That is, a digestion time 6 to 12 times longer in comparison to that required by SON Formula®. As a result, it can be concluded that SON Formula® requires a digestion time that is 6 to 12 times shorter in comparison to that of any dietary protein, protein supplement or amino acid formula.

Clocks showing digestion times for SON Formula and dietary proteins.

Considering the scientific evidence1-4 previously described, it can be concluded and confirmed that SON Formula® is the most nutritious in comparison to any dietary protein, protein supplement or amino acid formula.

3. The use of SON Formula® releases only 1% nitrogen catabolites, namely metabolic toxic waste. That is, the lowest amount of nitrogen catabolites ever released, in comparison to any dietary protein, protein supplement or amino acid formula.

Comparative clinical studies performed in human subjects1-4 have shown that the use of SON Formula® releases only 1% nitrogen catabolites. In contrast, dietary proteins release, during digestion, 68 to 84% nitrogen catabolites. That is, 67 to 83 times more metabolic toxic waste, to be catabolized through the hepatic and renal function. As a result, it can be concluded that the use of SON Formula® releases 67 to 83 times less nitrogen catabolites, meaning metabolic toxic waste, in comparison to any dietary protein, protein supplement or amino acid formula.  

Graph showing nitrogen catabolites released by SON Formula and dietary proteins.

Considering the scientific evidence1-4 previously described, it can be concluded that the use of SON Formula® is the safest and therefore the most health-preserving in comparison to any dietary protein, protein supplement or amino acid formula.

4. The use of SON Formula® provides only 0.04 kcal/g. That is, the lowest amount ever of kcal/g in comparison to any dietary protein, protein supplement or amino acid formula.

Comparative clinical studies performed in human subjects1-4 have shown that the use of SON Formula® provides only 0.04 kcal/g. In contrast, dietary proteins, provide 4 kcal/g. That is, 99 times more kilocalories per gram in comparison to those provided by SON Formula®. As a result, it can be concluded that SON Formula® provides 99 times less kilocalories per gram in comparison to any dietary protein, protein supplement or amino acid formula.

Considering the scientific evidence1-4 previously described, it can be concluded and confirmed that the use of SON Formula® is the safest and therefore the most health-preserving in comparison to any dietary protein, protein supplement or amino acid formula.

5. SON Formula®, in contrast to any dietary protein or protein supplement contains no protein, lipid, carbohydrate, vitamin, mineral, trace element or excipient.

SON Formula® contains only the active ingredient map master amino acid pattern®, and it does not contain any inactive ingredient or excipient. As a result, the use of SON Formula® in substitution for dietary proteins, allows for unprecedented efficacy and flexibility to provide only the required amounts of macronutrients and micronutrients. Thus, preventing or minimizing the consumption of the contraindicated ones.

Considering the scientific evidence1-4 previously described, it can be concluded and confirmed that the use of SON Formula® allows for an easier and more efficient clinical nutrition management, to prevent or limit the intake of any non-required macronutrient or micronutrient.

6. The sixth and last unique characteristic of SON Formula® is originated from the cumulative effects of its, previously described, five unique characteristics. Therefore, the use of SON Formula®, in substitution for dietary proteins, protein supplements, or amino acid formulas, can significantly reduce renal, hepatic, pancreatic, digestive, cardiovascular, and/or respiratory load, in comparison to any dietary protein, protein supplement or amino acid formula.

CONCLUSIONS

The scientific evidence shown in forty-five published comparative clinical studies, conducted in human subjects, while ingesting SON Formula®, as a partial or total substitute for dietary proteins, has shown and confirmed that the use of SON Formula® is:

  • the most nutritious and the most health-preserving

in comparison to any dietary protein, protein supplement, or amino acid formula.


SON Formula® vs. Dietary Proteins & Protein Supplements
Characteristics SON Formula® Dietary Proteins Protein Supplements
Net Nitrogen Utilization (%NNU) 99% NNU 32% NNU (average) 16% NNU (average)
Digestion Time 23 min 180-360 min (3-6 hrs)
6-12 times longer
180-360 min (3-6 hrs)
6-12 times longer
Body Protein Synthesis
(BPS = %NNU/min)
99% NNU/23 min 24-48 times lower 48-96 times lower
Released Nitrogen Catabolites (%) 1% 68% (average) 84% (average)
Energy = kcal/g 0.04 kcal/g 4 kcal/g 4 kcal/g
Fecal residue Absent Present Present
Contraindications None Renal Failure and/or Hepatic Failure Renal Failure and/or Hepatic Failure
Adverse Reactions None Food Sensitivities Food Sensitivities
Refrigeration Not Needed Needed N/A